From what I know from the desert gene is that it is not perticulairy this combo but the problem with the desert gene even as a stand alone gene. Desert is not lethal but the females can not reproduce. It seems no-one ever managed to get babies from a desert female. The eggs either don’t get fertilized and get resolved in the body of the female and never get out, or they do grow but the female can not lay the eggs and gets egg bound with all the problems you can think off, so dying or needing surgery to save the snake. With the males is nothing wrong. But if they get babies and they are female you can only sell them as pets and not as breeders.
There is a whole video of Justin kobylka on youtube in which he did try it to see if it was true. The one female that did get full term eggs, ended up having surgery to save her life so he and most breeders stopped trying. I heard several breeders on youtube mentioning that since the discovery of the ultramel, which is almost the same visually almost no breeder wants to breed them anymore because 50 % of the offspring can only be sold as a pet and there is a healty alternative for it. Just like there is now a shift going on from super cinnamon/super blackpastel / black pastel cinnamon because of the kinking to super mahogany ( Suma’s) to get the black snakes because there is no genetic problem with suma’s.
This is about the desert gene. The desert ghost is totally fine.