Be snarky if you want, but it’s super obvious. Wash yourself in only warm water for a week and you’ll quickly learn the difference. You don’t have to be a rocket surgeon to be able to tell the difference between a prekilled, thawed, or live mouse: sniff one of each.
I hope I’ve made that point quite clear already.
Outside of how water works… that has always been the point. There are people willing to debate that the smell of the brains/spinal fluid/cranial fluid/whatever are the thing that “does it” for ball pythons as some sort of natural attractant. I’m unconvinced. Colubrids, etc, seems like it could be a possibility and at least one other member has agreed. I’d still suggest chicken hearts or other scenting first.
The conversation started because I wanted to point it out as a thing to generally avoid. It was an extremely common suggestion, technically still is, and I’m pretty sure it comes from when we had a lot of wild caught animals. I could be wrong.
In the case of the short tailed pythons… if you have one that stops eating… it’s because something has gone wrong with the enclosure. Definitely similar considerations for ball pythons. Hides, prey size, heating up the food item, etc, are all great things to try.
Crushing mouse skulls is just wasted effort that can mask other problems. For this and many other reasons I absolutely suggest that new keepers avoid something like this. That was the point.